Vikos gorge lies in the southern slopes of Mount Tymphi with a length of about 20 km, depth ranging from 120 to 490 m, and a width ranging from 400 m to only a few meters at its narrowest part.

The gorge collects the waters of a number of small rivers and leads them into the Voidomatis River which forms in the gorge.

There is a natural viewing platform over the deepest part of the gorge at Oxia, a location 3 km by a newly constructed road from the village of Monodendri. Another viewpoint over the gorge is at Beloi, on the eastern side of the gorge, accessible from the village of Vradeto.